The kidneys are two bean-shaped organs found on the left and right in the retroperitoneal space in the humans. The nephron is the structural and functional unit of the kidney. The kidneys excrete a variety of waste products through filtration, reabsorption, secretion and excretion produced by metabolism into the urine. Here are some boggling facts about kidneys.

• Kidneys have a higher blood flow compared to the brain and liver. They reabsorb and redistribute 99% of the blood volume across the body, leaving the 1% of the filtered blood to become urine.
• You don’t need both, but only need one kidney to live a full, healthy life. And also, a single kidney with only 75 percent of its functional capacity can sustain life very well.
• The largest kidney stone ever recorded was the size of a coconut. It weighed a whopping 2.5 pounds (1.1 kilograms).
• Kidneys also pump around 400 gallons of blood every day thus filtering all the blood in your body from 20 to 25 times per day and in doing so keep the blood’s components stable.
• Kidneys can also activate vitamin D in your body – but only as a last line of defense. The liver takes over to produce vitamin D if your skin cells are unable to receive them from the Sun. But kidneys get the job done even if your liver can’t produce vitamin D.
• Your body contains 1.15 million nephrons in your body which are about 5 miles (8 kilometers) long when stretched out from one end to the other.
• You pee between one and two liters of urine every day and you can hold anywhere between 50 and 500 milliliters of urine in your bladder.

About 13 percent of U.S. adults have CKD and the leading causes are diabetes and high blood pressure, which cause an estimated 44 percent and 28 percent, respectively, of new U.S. kidney failure cases.

Journal of Clinical & Experimental Nephrology focuses on the dissemination of the latest  advancements on the current knowledge on all the aspects of Nephrology such as Peritoneal Dialysis, Kidney Diseases, Acute Renal Replacement Therapy, Chronic Kidney Disease, End-Stage Renal Diseases, Lupus Nephritis and Renal Transplantation.