psychoactive drug use and addiction

Image

Dual Diagnosis: Open Access is an peer-reviewed, open-access scholarly journal focused on publishing articles in all aspects of academic journal and aims to publish most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide.

Drug addiction is a psychiatric disorder based on a dysfunction of the brain. It frequently develops from a controlled drug consumption and drug instrumentalization (DI). Thereby, DI is the use of a drug to improve specific non-drug related behaviors, beyond the drug’s direct positive or negative reinforcing effects. Currently available pharmacotherapies for drug addiction show low effect size and rather limited long-term efficacy, which suggests that current theories on addiction are still insufficient in how they capture the phenomenon and how they allow predictions for highly efficient treatments.

This opinion review attempts a critical analysis of some aspects of current addiction neuroscience using animal models. As a result, (1) animal models that cover previously neglected types of drug memories in controlled drug use are suggested. (2) Animal models for drug instrumentalization are warranted. Animal models of drug addiction should consider that addiction develops predominantly in individuals with mental and/or environmental challenges. It is suggested (3) to preferentially use animal models with similar mental and environmental challenges to model the transition of controlled to compulsive drug use. (4) Animal models should in the future also capture the important aspect of the motivation to self-medicate in order to ameliorate a negative emotional/physical state.

Potential pharmaco-treatments of addiction, in order to later achieve compliance in humans, should be tested for their systemic self-administration in order to self-medicate a drug-induced aversive state. This may allow a better understanding of the fundamental differences between an organism that shows controlled psychoactive drug consumption as an integral part of a ‘normal’ behavioral repertoire and one in a pathological condition with compulsive drug abuse.

The journal offers author benefits which include:

  • The copyright of their own research outcomes, concepts and expert opinions
  • Post-publication promotion of the published articles for enhanced visibility and citation probability
  • Special discounts on processing charges based on the number, relevance and impact of the submissions
  • Publication of the article within one week after the acceptance by the peer-reviewers (fast track review)

Journal accepts original manuscripts in the form of Research Articles, Review Articles, Clinical Reviews, Commentaries, Case Reports, Perspectives and Short Communications .

You can Submit manuscript directly online https://www.imedpub.com/submissions/dual-diagnosis-open-access.html or as an attachment to this E-mail: dualdiagnosis@emedsci.com

Articles will be paid high attention during the Publication any immediate submission is highly appreciable.

Regards,
Nancy Ella
Journal Editor
Dual Diagnosis: Open Access
WhatsApp: +1-947-333-4405